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Archives of Disease in Childhood

Archives of Disease in Childhood: intellectual conflicts of interest in youth sex-rejecting guidelines

Sep 20, 2026 · Research
Editorial still life of an open medical journal, spilled ink, a brass scale, and a sealed burgundy guideline binder

Archives of Disease in Childhood, a BMJ journal, published Intellectual conflicts of interest and the ongoing controversy on guidelines regarding gender-affirming care online on 18 September 2026. The paper’s phrase “gender-affirming care” means puberty blockers and opposite-sex hormones for children and adolescents with gender dysphoria.

The author is Dr. Richard Santen, Internal Medicine, University of Virginia School of Medicine. His competing-interests statement identifies him as a past president of the Endocrine Society.

The article addresses intellectual conflicts of interest in those clinical guidelines, including how a weak evidence base is filled by conflicted “expert opinion.”

Primary source. Archives of Disease in Childhood (BMJ). DOI 10.1136/archdischild-2025-328741. PubMed 42759992.

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